Plant Transcription Factor Database
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G46090.1
Common NameF12M12.60, ZAT7
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C2H2
Protein Properties Length: 168aa    MW: 18359.2 Da    PI: 9.2526
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G46090.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
      zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                  ++Cp+Cg  F+    L  H+r+H
                  78********************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576674.96E-53663No hitNo description
PfamPF139128.6E-123964IPR007087Zinc finger, C2H2
SMARTSM0035514062IPR015880Zinc finger, C2H2-like
PROSITE profilePS501578.9954062IPR007087Zinc finger, C2H2
PROSITE patternPS0002804262IPR007087Zinc finger, C2H2
SuperFamilySSF576676.1E-684113No hitNo description
PfamPF139121.1E-1086109IPR007087Zinc finger, C2H2
SMARTSM003550.05886108IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.38886113IPR007087Zinc finger, C2H2
PROSITE patternPS00028088108IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010200Biological Processresponse to chitin
GO:0045926Biological Processnegative regulation of growth
GO:0080134Biological Processregulation of response to stress
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008270Molecular Functionzinc ion binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
Sequence ? help Back to Top
Protein Sequence    Length: 168 aa     Download sequence    Send to blast
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.197630.0root| seed
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasAT3G46090
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, stems and leaves. {ECO:0000269|PubMed:9132053}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in oxidative stress response. {ECO:0000269|PubMed:14722088}.
Function -- GeneRIF ? help Back to Top
  1. the EAR-domain of Cys2/His2-type zinc finger proteins plays a key role in the defense response of Arabidopsis to abiotic stresses
    [PMID: 17259181]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
Motif logo
Cis-element ? help Back to Top
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By H(2)O(2), heat stress, wounding and cucumber mosaic virus (CMV). {ECO:0000269|PubMed:14722088, ECO:0000269|PubMed:18922600}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT5G59820 (A)
Interaction ? help Back to Top
Source Intact With
IntActSearch Q42453
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G46090
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAL3557750.0AL355775.1 Arabidopsis thaliana DNA chromosome 3, BAC clone F12M12.
GenBankBT0248700.0BT024870.1 Arabidopsis thaliana At3g46090 gene, complete cds.
GenBankCP0026860.0CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.
GenBankHQ6983080.0HQ698308.1 Arabidopsis thaliana ecotype Landsberg erecta chromosome 3 genomic sequence.
GenBankX986760.0X98676.1 A.thaliana mRNA for ZAT7 protein.
GenBankX986770.0X98677.1 A.thaliana zat7 gene.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_190195.11e-121zinc finger protein ZAT7
SwissprotQ424531e-123ZAT7_ARATH; Zinc finger protein ZAT7
TrEMBLD7LMV25e-87D7LMV2_ARALL; Putative uncharacterized protein
STRINGAT3G46090.11e-120(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP13115149
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
  2. Menges M,Hennig L,Gruissem W,Murray JA
    Cell cycle-regulated gene expression in Arabidopsis.
    J. Biol. Chem., 2002. 277(44): p. 41987-2002
  3. Rizhsky L,Davletova S,Liang H,Mittler R
    The zinc finger protein Zat12 is required for cytosolic ascorbate peroxidase 1 expression during oxidative stress in Arabidopsis.
    J. Biol. Chem., 2004. 279(12): p. 11736-43
  4. Goda H, et al.
    Comprehensive comparison of auxin-regulated and brassinosteroid-regulated genes in Arabidopsis.
    Plant Physiol., 2004. 134(4): p. 1555-73
  5. Englbrecht CC,Schoof H,B
    Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.
    BMC Genomics, 2004. 5(1): p. 39
  6. Stanley Kim H, et al.
    Transcriptional divergence of the duplicated oxidative stress-responsive genes in the Arabidopsis genome.
    Plant J., 2005. 41(2): p. 212-20
  7. AbuQamar S, et al.
    Expression profiling and mutant analysis reveals complex regulatory networks involved in Arabidopsis response to Botrytis infection.
    Plant J., 2006. 48(1): p. 28-44
  8. Ciftci-Yilmaz S, et al.
    The EAR-motif of the Cys2/His2-type zinc finger protein Zat7 plays a key role in the defense response of Arabidopsis to salinity stress.
    J. Biol. Chem., 2007. 282(12): p. 9260-8
  9. Libault M,Wan J,Czechowski T,Udvardi M,Stacey G
    Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.
    Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11
  10. Abercrombie JM, et al.
    Transcriptional responses of Arabidopsis thaliana plants to As (V) stress.
    BMC Plant Biol., 2008. 8: p. 87
  11. Mitsuya Y, et al.
    Spermine signaling plays a significant role in the defense response of Arabidopsis thaliana to cucumber mosaic virus.
    J. Plant Physiol., 2009. 166(6): p. 626-43
  12. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
  13. Meissner R,Michael AJ
    Isolation and characterisation of a diverse family of Arabidopsis two and three-fingered C2H2 zinc finger protein genes and cDNAs.
    Plant Mol. Biol., 1997. 33(4): p. 615-24